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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. MRE11A, MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
Sequence ID:NM_005590
RefSeqGene ID:NG_007261
Entrez Gene ID:4361
Ensembl ID:ENSG00000020922

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 94153050 - 94227010

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5181691Full LengthBC063458MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
4687479IncompleteBC017823MRE11 meiotic recombination 11 homolog A (S. cerevisiae)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005582  NP_005581  

Protein Infomation

NM_005590 NP_005581   Metallophos
NM_005591 NP_005582 P49959 Metallophos

Related Sequences

AF073362 AAC36249 P49959
U37359 AAC78721 P49959
AF022778 AAD10197 P49959
BC005241 AAH05241 Q9BS79
BC017823 AAH17823 Q05D78
BC063458 AAH63458 P49959
BT006730 AAP35376 Q9BS79
JF432288 ADZ15505  
AK095388 BAG53039 B3KTC7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MRE11A NP_005582 M.musculus Mre11a 17535 Gene Info NP_061206 89
R.norvegicus Mre11a 64046   NP_071615 89
S.pombe rad32 2542757   NP_592935 47
S.cerevisiae MRE11 855264   NP_013951 45
A.gambiae AgaP_AGAP006797 1270268   XP_308950 43
A.thaliana MRE11 835514   NP_200237 43
D.melanogaster mre11 34565   NP_523547 43
N.crassa NCU08730 3879754   XP_963591 43
C.elegans mre-11 179488   NP_505736 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta