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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HNF1B, HNF1 homeobox B
Sequence ID:NM_000458
NM_001165923
NM_006481
RefSeqGene ID:NG_013019
Entrez Gene ID:6928
Ensembl ID:ENSG00000108753

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DIABETES MELLITUS, NON-INSULIN-DEPENDENTABCC8
AKT2
CDKAL1
ENPP1
GCGR
GCK
GPD2
HMGA1
HMGA1
HNF1A
HNF4A
IGF2BP2
IL6
IRS1
IRS2
KCNJ11
LIPC
MAPK8IP1
MTNR1B
NEUROD1
NEUROD1
NEUROD1
PAX4
PDX1
PPARG
PTPN1
RETN
SLC2A4
SLC30A8
TCF7L2
VEGFA
WFS1
WFS1
PROSTATE CANCERAR
BRCA2
CD82
CDH1
CHEK2
CHEK2
ELAC2
HIP1
HIP1
KLF6
KLF6
MAD1L1
MSR1
MXI1
MXI1
PTEN
TUSC3
TUSC3
ZFHX3
RENAL CARCINOMA, CHROMOPHOBE, SOMATICDIRC2
FLCN
HNF1A
OGG1
RNF139
VHL
RENAL CYSTS AND DIABETES SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 36047297 - 36105050

 Exon Info From UCSC:
NM_000458
NM_001165923

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4414015Full LengthBC017714HNF1 homeobox B

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000449  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000458 NP_000449 Q6FHW6
P35680
HNF-1B_C
HNF-1_N
NM_001165923 NP_001159395    

Related Sequences

 
mRNAGenPeptSwissProt
BC017714 AAH17714 Q6FHW6
P35680
BT007126 AAP35790 Q6FHW6
P35680
DQ891528 ABM82454  
EU176615 ABW03416  
HM116553 ADM43490 E0YMJ6
HM116554 ADM43491 E0YMJ7
HM116555 ADM43492 E0YMJ8
HM116556 ADM43493 E0YMJ9
AK290131 BAF82820 Q6FHW6
AK296633 BAG59235 P35680
AK298393 BAG60628 B4DPL6
X58840 CAA41652 Q6FHW6
P35680
X71348 CAB59223 P35680
CR536572 CAG38809 Q6FHW6
P35680

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HNF1B NP_000449 R.norvegicus Hnf1b 25640   NP_037235 97
M.musculus Hnf1b 21410 Gene Info NP_033356 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)