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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. GPNMB, glycoprotein (transmembrane) nmb
Sequence ID:NM_001005340
Entrez Gene ID:10457
Ensembl ID:ENSG00000136235

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7p15Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 23286420 - 23314727

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5177095Full LengthBC032783glycoprotein (transmembrane) nmb
4877773IncompleteBC025297glycoprotein (transmembrane) nmb

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001005340  NP_002501  

Protein Infomation

NM_001005340 NP_001005340 Q14956 PKD
NM_002510 NP_002501   PKD

Related Sequences

AF322909 AAG42839 Q14956
BC011595 AAH11595 Q96F58
BC032783 AAH32783 Q14956
BT007074 AAP35737 Q96F58
AY359124 AAQ89481 Q14956
DQ892084 ABM83010  
DQ895277 ABM86203  
AK292078 BAF84767 A8K7R3
AK312279 BAG35208 B2R5R1
AK296779 BAG59357 B4DKZ5
AK297031 BAG59559 B4DLJ7
AK297051 BAG59577 B4DLL5
AK297055 BAG59580 B4DLL8
AK297803 BAG60141 B4DN79
AK303071 BAG64187 B4DZS5
AK304671 BAG65446 B4E3D4
X76534 CAA54044 Q14956
AJ505015 CAD43718 Q8IXJ5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens GPNMB NP_001005340 M.musculus Gpnmb 93695 Gene Info NP_444340 72
R.norvegicus Gpnmb 113955   NP_579832 70

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)