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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. POMC, proopiomelanocortin
Sequence ID:NM_000939
NM_001035256
RefSeqGene ID:NG_008997
Entrez Gene ID:5443
Ensembl ID:ENSG00000115138

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
OBESITYADRB2
ADRB3
AGRP
CARTPT
ENPP1
FTO
GHRL
MC3R
MC4R
NR0B2
PPARG
PPARGC1B
PYY
SDC3
SIM1
UCP1
UCP2
UCP3
UCP3
OBESITY, ADRENAL INSUFFICIENCY, AND RED HAIR DUE TO POMC DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p23.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 25383789 - 25391402

 Exon Info From UCSC:
NM_000939
NM_001035256

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30392189Full LengthBC065832proopiomelanocortin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000930  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000939 NP_000930 P01189 ACTH_domain
Op_neuropeptide
NPP
NM_001035256 NP_001030333 P01189  

Related Sequences

 
mRNAGenPeptSwissProt
M25896 AAA35799 P01189
M28636 AAA60139 Q6LDP0
M38297 AAA60140 P01189
S76492 AAC60644 Q53WY7
BC065832 AAH65832 P01189
BT019918 AAV38721 Q5TZZ7
DQ884404 ABI63371 A6XND7
CR541826 CAG46625 Q6FHC8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens POMC NP_000930 R.norvegicus Pomc 24664   NP_647542 83
M.musculus Pomc 18976 Gene Info NP_032921 82

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)