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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CRBN, cereblon
Sequence ID:NM_001173482
NM_016302
RefSeqGene ID:NG_016864
Entrez Gene ID:51185
Ensembl ID:ENSG00000113851

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 2 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p26.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 3192214 - 3221365

 Exon Info From UCSC:
NM_001173482
NM_016302

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4672890Full LengthBC017419cereblon
5264951Full LengthBC067811cereblon

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001173482 NP_001166953    
NM_016302 NP_057386 Q96SW2  

Related Sequences

 
mRNAGenPeptSwissProt
AF117230 AAF17211 Q96SW2
BC017419 AAH17419 Q96SW2
BC067811 AAH67811 Q96SW2
HQ447457 ADQ31943  
JF432198 ADZ15415  
AK027507 BAB55162 Q96SW2
AK312577 BAG35471 Q96SW2
AK301423 BAG62951 B4DW89
CR627060 CAH10361 Q96SW2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CRBN NP_057386 M.musculus Crbn 58799 Gene Info NP_780566 96
R.norvegicus Crbn 297498   NP_001015003 96
A.thaliana AT2G25740 817117   NP_850069 35
A.gambiae AgaP_AGAP005299 1270386   XP_309090 31
D.melanogaster CG3925 41230   NP_649973 31

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)