Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TWF1, twinfilin, actin-binding protein, homolog 1 (Drosophila)
Sequence ID:NM_001242397
NM_002822
NR_073472
NR_073473
NM_198974
Entrez Gene ID:5756
Ensembl ID:ENSG00000151239

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 44189295 - 44200052

Transcript StartTranscript EndChromosomal Start Chromosomal End
2320534418752744189557
205421754419077844190899
217623264419110444191254
232724524419151044191635
245325574419320044193304
255826534419423744194332
265428324419608844196266
283329104419829744198374
291130654420002344200177

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4249251Full LengthBC022344twinfilin, actin-binding protein, homolog 1 (Drosophila)
5297068Full LengthBC043148twinfilin, actin-binding protein, homolog 1 (Drosophila)
30346906IncompleteBC068548twinfilin, actin-binding protein, homolog 1 (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002813  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001242397 NP_001229326    
NM_002822 NP_002813 Q12792 Cofilin_ADF

Related Sequences

 
mRNAGenPeptSwissProt
U02680 AAC50062 Q12792
BC022344 AAH22344 Q12792
BC043148 AAH43148 Q12792
BC068548 AAH68548 Q12792
BT019691 AAV38497 Q12792
EU832214 ACE86784  
EU832120 ACE87470  
AB209302 BAD92539 Q12792
AK291223 BAF83912 Q12792
AK127868 BAG54588 Q12792
AK297206 BAG59691 Q12792
CR541736 CAG46536 Q12792
CR541761 CAG46561 Q12792

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TWF1 NP_001229326 R.norvegicus Twf1 315265   NP_001008521 95
M.musculus Twf1 19230 Gene Info NP_032997 95
A.gambiae AgaP_AGAP003717 1271450   XP_310245 52
A.gambiae TWF_ANOGA 3290886   XP_310246 51
D.melanogaster twf 41719   NP_650338 49
C.elegans F38E9.5 181711   NP_510669 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)