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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PCSK9, proprotein convertase subtilisin/kexin type 9
Sequence ID:NM_174936
RefSeqGene ID:NG_009061
Entrez Gene ID:255738
Ensembl ID:ENSG00000169174

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HYPERCHOLESTEROLEMIA, FAMILIAL, 3 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p32.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 55505221 - 55530523

 Exon Info From UCSC:
NM_174936

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100066345Full LengthBC166619proprotein convertase subtilisin/kexin type 9
5767792IncompleteBC042095proprotein convertase subtilisin/kexin type 9

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_777596  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_174936 NP_777596 Q8NBP7 Peptidase_S8
Subtilisin_N

Related Sequences

 
mRNAGenPeptSwissProt
BC166619 AAI66619 Q8NBP7
EF692496 ABV59216 Q8NBP7
AK075365 BAC11572 Q8NBP7
AK124635 BAC85910 Q8NBP7
AK293870 BAG57260 B4DEZ9
AK297473 BAG59894 B4DMI2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PCSK9 NP_777596 M.musculus Pcsk9 100102 Gene Info NP_705793 77
R.norvegicus Pcsk9 298296   NP_954862 77
N.crassa NCU07159 3873522   XP_957384 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)