Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. THRB, thyroid hormone receptor, beta
Sequence ID:NM_000461
NM_001128176
NM_001128177
NM_001252634
RefSeqGene ID:NG_009159
Entrez Gene ID:7068
Ensembl ID:ENSG00000151090

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
THYROID HORMONE RESISTANCE 
THYROID HORMONE RESISTANCE, SELECTIVE PITUITARY 
THYROID HORMONE RESISTANCE,AUTOSOMAL RECESSIVE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p24.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 24174830 - 24231827

 Exon Info From UCSC:
NM_000461
NM_001128176
NM_001128177

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40033198Full LengthBC106929thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
40033200Full LengthBC106930thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
4479351IncompleteBC028910thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000452  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000461 NP_000452 P10828 Hormone_recep
zf-C4
NM_001128176 NP_001121648    
NM_001128177 NP_001121649    
NM_001252634 NP_001239563    

Related Sequences

 
mRNAGenPeptSwissProt
M26747 AAA35677 P10828
BC106929 AAI06930 P10828
BC106930 AAI06931 P10828
AY286465 AAQ23704 P10828
AY286466 AAQ23705 P10828
AY286467 AAQ23706 P10828
AY286468 AAQ23707 P10828
AY286469 AAQ23708 P10828
AY286470 AAQ23709 P10828
AY286471 AAQ23710 P10828
EU446664 ABZ92193  
GQ919288 ADK27482 E0XAW8
HQ692825 ADZ17336 F1D8N7
AK096628 BAG53341 P10828
AB307687 BAH02278 B6ZGR7
X04707 CAA28412 P10828
X74497 CAA52606 P10828

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens THRB NP_000452 M.musculus Thrb 21834 Gene Info NP_001106888 97
R.norvegicus Thrb 24831   NP_036804 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta