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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. LRRK2, leucine-rich repeat kinase 2
Sequence ID:NM_198578
RefSeqGene ID:NG_011709
Entrez Gene ID:120892
Ensembl ID:ENSG00000188906

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 40758728 - 40763083

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40125731Full LengthBC117180leucine-rich repeat kinase 2

Protein Infomation

NM_198578 NP_940980 Q5S007 EC  

Related Sequences

BC117180 AAI17181 Q17RV3  
AY792511 AAV63975 Q5S007 EC
AL834529 CAD39185 Q5S007 EC
BX640975 CAE45989 Q6MZN9  
BR000408 FAA00322 A2VED2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens LRRK2 NP_940980 M.musculus Lrrk2 66725 Gene Info NP_080006 87
R.norvegicus Lrrk2 300160   XP_235581 87

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)