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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SPG7, spastic paraplegia 7 (pure and complicated autosomal recessive)
Sequence ID:NM_003119
NM_199367
RefSeqGene ID:NG_008082
Entrez Gene ID:6687
Ensembl ID:ENSG00000197912

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q24.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 89574818 - 89604129

 Exon Info From UCSC:
NM_003119
NM_199367

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5274587Full LengthBC036104spastic paraplegia 7 (pure and complicated autosomal recessive)
3956605IncompleteBC007692spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive)
4396303IncompleteBC035929spastic paraplegia 7 (pure and complicated autosomal recessive)
6257443IncompleteBC052587spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003110  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003119 NP_003110 Q9UQ90 AAA
Peptidase_M41
FtsH_ext
NM_199367 NP_955399    

Related Sequences

 
mRNAGenPeptSwissProt
S54769 AAB25303  
AF034795 AAC02429 O43535
AF090912 AAF24033 Q9UI71
BC035929 AAH35929 Q9UQ90
BC036104 AAH36104 Q9UQ90
EU832769 ACE87780  
GQ129312 ACT64446  
AK094627 BAG52898 B3KSY6
Y16610 CAA76314 Q9UQ90

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SPG7 NP_003110 M.musculus Spg7 234847 Gene Info NP_694816 89
R.norvegicus Spg7 353231   NP_852053 88
D.melanogaster CG2658 31253   NP_570017 60
A.gambiae AgaP_AGAP000560 1271665   XP_310523 55
C.elegans ppgn-1 177021   NP_500191 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)