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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CYP11B1, cytochrome P450, family 11, subfamily B, polypeptide 1
Sequence ID:NM_000497
NM_001026213
RefSeqGene ID:NG_007954
Entrez Gene ID:1584
Ensembl ID:ENSG00000160882

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ADRENAL HYPERPLASIA, CONGENITAL, DUE TO 11-BETA-HYDROXYLASEDEFICIENCY 
ALDOSTERONISM, GLUCOCORTICOID-REMEDIABLE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:8q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 143955215 - 143961236

 Exon Info From UCSC:
NM_000497
NM_001026213

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40007097Full LengthBC096285cytochrome P450, family 11, subfamily B, polypeptide 1
40007098Full LengthBC096286cytochrome P450, family 11, subfamily B, polypeptide 1
40007100Full LengthBC096287cytochrome P450, family 11, subfamily B, polypeptide 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001021384  NP_000488  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000497 NP_000488 P15538 EC 1.14.15.4 p450
NM_001026213 NP_001021384     p450

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M24667 AAA52148 P15538 EC 1.14.15.4
BC096285 AAH96285 Q4VAR0  
BC096286 AAH96286 P15538 EC 1.14.15.4
BC096287 AAH96287 P15538 EC 1.14.15.4
AF478474 AAL84813 Q8TDD0  
AK094090 BAC04283 Q8N9P8  
X55764 CAA39290 P15538 EC 1.14.15.4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CYP11B1 NP_000488 R.norvegicus Cyp11b2 24294   NP_036670 69
M.musculus Cyp11b2 13072 Gene Info NP_034121 68

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)