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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ADD1, adducin 1 (alpha)
Sequence ID:NM_001119
NM_014189
NM_014190
NM_176801
RefSeqGene ID:NG_012037
Entrez Gene ID:118
Ensembl ID:ENSG00000087274

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
HYPERTENSIONAGT
AGTR1
AGTR1
ATP1B1
ATP1B1
CYP3A5
ECE1
GNB3
NOS2
NOS3
PTGIS
RGS5
RGS5
SELE

Cytogenetic Location (from UniGene)

Cytogenetic Location:4p16.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 2845619 - 2930250

 Exon Info From UCSC:
NM_001119
NM_014189
NM_014190
NM_176801

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3532276Full LengthBC013393adducin 1 (alpha)
5297337Full LengthBC042998adducin 1 (alpha)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_054908  NP_054909  NP_001110  NP_789771  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001119 NP_001110 P35611 Aldolase_II
NM_014189 NP_054908   Aldolase_II
NM_014190 NP_054909   Aldolase_II
NM_176801 NP_789771   Aldolase_II

Related Sequences

 
mRNAGenPeptSwissProt
S70312 AAB30913 Q16155
BC013393 AAH13393 Q96D30
BC042998 AAH42998 Q86XM2
AK295457 BAG58391 B4DI79
AK298523 BAG60726 B4DPW4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ADD1 NP_054908 M.musculus Add1 11518 Gene Info NP_001019629 93
R.norvegicus Add1 24170   NP_058686 92
A.gambiae AgaP_AGAP004852 1275115   XP_314339 41
C.elegans add-1 180760   NP_001024640 41
D.melanogaster hts 37230   NP_725888 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta