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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PRPF8, PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)
Sequence ID:NM_006445
RefSeqGene ID:NG_009118
Entrez Gene ID:10594
Ensembl ID:ENSG00000174231

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:17p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 1553923 - 1588100

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5587081Full LengthBC064370PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)
3342958IncompleteBC000579PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006436  

Protein Infomation

NM_006445 NP_006436 Q6P2Q9 Mov34

Related Sequences

AF092565 AAC61776 Q6P2Q9
BC064370 AAH64370 Q6P2Q9
AY486134 AAS64747 Q6JH03
AY486135 AAS64748 Q6JH02
AB007510 BAA22563 Q6P2Q9
AK222905 BAD96625 Q53GM6
AK296344 BAG59028 B4DK16

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PRPF8 NP_006436 R.norvegicus Prpf8 287530   XP_213385 100
M.musculus Prpf8 192159 Gene Info NP_619600 100
A.gambiae AgaP_AGAP006885 1270195   XP_308873 93
D.melanogaster Prp8 36304   NP_610735 92
C.elegans prp-8 176153   NP_498785 87
A.thaliana SUS2 844347   NP_178124 83
A.thaliana AT4G38780 830033   NP_195589 81
S.pombe spp42 2543413   NP_593861 74
P.falciparum PFD0265w 812426   XP_001351366 74
N.crassa NCU07832 3879101   XP_962953 73
S.cerevisiae PRP8 856570   NP_012035 63

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)