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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PKD2, polycystic kidney disease 2 (autosomal dominant)
Sequence ID:NM_000297
RefSeqGene ID:NG_008604
Entrez Gene ID:5311
Ensembl ID:ENSG00000118762

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
POLYCYSTIC KIDNEY DISEASE 2 

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q22.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 88996726 - 88998926

 Exon Info From UCSC:
NM_000297

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8327729Full LengthBC112261polycystic kidney disease 2 (autosomal dominant)
8327731Full LengthBC112263polycystic kidney disease 2 (autosomal dominant)
40080643BC111454polycystic kidney disease 2 (autosomal dominant)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000288  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000297 NP_000288 Q13563 efhand
PKD_channel

Related Sequences

 
mRNAGenPeptSwissProt
AF054992 AAC09351 Q9UEU6
U50928 AAC50520 Q13563
U56813 AAC50933 Q13563
BC111454 AAI11455  
BC112261 AAI12262 Q13563
BC112263 AAI12264 Q13563
AK293461 BAG56956 B4DE45
AK294173 BAG57494 B4DFN3
AK294589 BAH11820 B7Z2D4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PKD2 NP_000288 M.musculus Pkd2 18764 Gene Info NP_032887 91
R.norvegicus Pkd2 498328   XP_573552 91
C.elegans pkd-2 178424   NP_502838 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)