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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LPL, lipoprotein lipase
Sequence ID:NM_000237
RefSeqGene ID:NG_008855
Entrez Gene ID:4023
Ensembl ID:ENSG00000175445

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
COMBINED HYPERLIPIDEMIA,FAMILIALUSF1
LIPOPROTEIN LIPASE DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:8p22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 19796763 - 19823632

NM_000237 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
14581979658119797038
4596191980569019805850
6207991980927919809458
8009111981082019810931
91211451981163019811863
114613881981335119813593
138915091981677019816890
151016921981841119818593
169317971981962519819729
179837461982282019824768

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4177781Full LengthBC011353lipoprotein lipase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000228  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000237 NP_000228 P06858 EC 3.1.1.34 Lipase
PLAT

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M15856 AAB59536 P06858 EC 3.1.1.34
BC011353 AAH11353 P06858 EC 3.1.1.34
BT006726 AAP35372 P06858 EC 3.1.1.34
DQ893541 ABM84467    
DQ893751 ABM84677    
AK222464 BAD96184 Q53HW6  
AK290290 BAF82979 A8K2M5  
AK312311 BAG35236 P06858 EC 3.1.1.34
AK092286 BAG52519 B3KRV7  
AK297164 BAH12512 B7Z4C6  
X14390 CAA32564 P06858 EC 3.1.1.34
X54516 CAA38372 P06858 EC 3.1.1.34
CR457054 CAG33335 Q6IAV0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LPL NP_000228 M.musculus Lpl 16956 Gene Info NP_032535 93
R.norvegicus Lpl 24539   NP_036730 92

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta