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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CFL2, cofilin 2 (muscle)
Sequence ID:NM_001243645
NM_021914
NM_138638
NR_028130
NR_028131
RefSeqGene ID:NG_012740
Entrez Gene ID:1073
Ensembl ID:ENSG00000165410

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
NEMALINE MYOPATHY 7 

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 35181216 - 35182768

 Exon Info From UCSC:
NM_021914
NM_138638

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4109108Full LengthBC022876cofilin 2 (muscle)
4245104Full LengthBC011444cofilin 2 (muscle)
4730117Full LengthBC022364cofilin 2 (muscle)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_619579  NP_068733  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001243645 NP_001230574    
NM_021914 NP_068733 Q9Y281
Q549N0
Cofilin_ADF
NM_138638 NP_619579 Q9Y281
Q549N0
Cofilin_ADF

Related Sequences

 
mRNAGenPeptSwissProt
AF134802 AAD31280 Q9Y281
Q549N0
AF134803 AAD31281 Q9Y281
Q549N0
BC011444 AAH11444 Q9Y281
Q549N0
BC022364 AAH22364 Q9Y281
Q549N0
BC022876 AAH22876 Q9Y281
Q549N0
AF087867 AAM10495 Q9Y281
Q549N0
EU832719 ACE87051  
EU832642 ACE87733  
AK314157 BAG36842 Q549N0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CFL2 NP_619579 M.musculus Cfl2 12632 Gene Info NP_031714 99

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)