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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PSMB8, proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
Sequence ID:NM_004159
NM_148919
RefSeqGene ID:NG_028165
Entrez Gene ID:5696
Ensembl ID:ENSG00000204264

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
AUTOINFLAMMATION, LIPODYSTROPHY, AND DERMATOSIS SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 32808493 - 32812428

 Exon Info From UCSC:
NM_004159
NM_148919

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2967119Full LengthBC001114proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_683720  NP_004150  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004159 NP_004150     Proteasome
NM_148919 NP_683720 P28062 EC 3.4.25.1 Proteasome

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U17496 AAA56777 P28062 EC 3.4.25.1
U17497 AAA56778 P28062 EC 3.4.25.1
BC001114 AAH01114 P28062 EC 3.4.25.1
AK300962 BAH13383 B7Z6U7  
X62598 CAA44482 P28062 EC 3.4.25.1
CR541661 CAG46462 Q6FHU0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PSMB8 NP_683720 M.musculus Psmb8 16913 Gene Info NP_034854 89
R.norvegicus Psmb8 24968   NP_542945 89

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta