Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MCM3, minichromosome maintenance complex component 3
Sequence ID:NM_001270472
NM_002388
Entrez Gene ID:4172
Ensembl ID:ENSG00000112118

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 52128815 - 52149517


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3542098Full LengthBC001626minichromosome maintenance complex component 3
3610786Full LengthBC003509minichromosome maintenance complex component 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002379  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001270472 NP_001257401      
NM_002388 NP_002379 P25205 EC 3.6.4.12 MCM

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC001626 AAH01626 P25205 EC 3.6.4.12
BC003509 AAH03509 P25205 EC 3.6.4.12
AY032603 AAK56392 Q8NHX6  
DQ893654 ABM84580    
DQ895840 ABM86766    
D38073 BAA07267 P25205 EC 3.6.4.12
AK222586 BAD96306 Q53HJ4  
AK312928 BAG35772 B2R7C5  
AK299566 BAG61508 B4DS46  
AK300754 BAG62421 B4DUQ9  
AK301704 BAG63176 B4DWW4  
X62153 CAA44078 P25205 EC 3.6.4.12

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MCM3 NP_002379 M.musculus Mcm3 17215 Gene Info NP_032589 94
R.norvegicus Mcm3 316273   XP_236988 93
A.gambiae AgaP_AGAP001135 1282031   XP_322026 67
D.melanogaster Mcm3 31449   NP_511048 64
S.cerevisiae MCM3 856680   NP_010882 54
N.crassa NCU08009 3878843   XP_962679 54
A.thaliana MCM3 834670   NP_199440 52
S.pombe mcm3 2538838   NP_587795 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta