Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. AK1, Adenylate kinase 1
Sequence ID:NM_000476
RefSeqGene ID:NG_011792
Entrez Gene ID:203
Ensembl ID:ENSG00000106992

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
HEMOLYTIC ANEMIA DUE TO ADENYLATE KINASE DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:9q34.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 130630286 - 130635342

NM_000476 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
31597130628760130630354
15981789130630599130630790
17901906130634101130634217
19072070130634968130635131
20712106130635304130635339
21072145130636889130636927
21462266130639901130640021

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2988248Full LengthBC001116adenylate kinase 1
30561924Full LengthBC100022adenylate kinase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000467  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000476 NP_000467 Q6FGX9
P00568
EC 2.7.4.3 ADK

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC001116 AAH01116 P00568 EC 2.7.4.3
BC100022 AAI00023 Q6FGX9
P00568
EC 2.7.4.3
BT019580 AAV38387 Q6FGX9
P00568
EC 2.7.4.3
DQ892576 ABM83502    
DQ895792 ABM86718    
AB021871 BAA78534 Q6FGX9
P00568
EC 2.7.4.3
AK223501 BAD97221 Q53EY8  
AK313758 BAG36497 Q6FGX9  
CR541977 CAG46775 Q6FGX9
P00568
EC 2.7.4.3
CR542004 CAG46801 Q6FGX9
P00568
EC 2.7.4.3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AK1 NP_000467 M.musculus Ak1 11636 Gene Info NP_067490 89
C.elegans F38B2.4 181317   NP_509884 60
A.gambiae AgaP_AGAP009317 1271227   XP_309986 51
D.melanogaster Adk1 39396   NP_729792 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)