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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PIK3C2A, phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
Sequence ID:NM_002645
Entrez Gene ID:5286
Ensembl ID:ENSG00000011405

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, skin, soft tissue, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p15.5-p14Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 17110866 - 17229530

 Exon Info From UCSC:
NM_002645

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8322710Full LengthBC113658phosphoinositide-3-kinase, class 2, alpha polypeptide

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002636  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002645 NP_002636 O00443 EC 2.7.1.154 C2
PI3_PI4_kinase
PI3Ka
PX
PI3K_C2
PI3K_rbd

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC113658 AAI13659 O00443 EC 2.7.1.154
HQ258691 ADR83442    
AK294416 BAG57666 B4DG55  
AK299474 BAG61438 B4DRX6  
AK304262 BAG65126 B4E2G4  
Y13367 CAA73797 O00443 EC 2.7.1.154

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PIK3C2A NP_002636 M.musculus Pik3c2a 18704 Gene Info NP_035213 90
R.norvegicus Pik3c2a 361632   NP_001101970 90
A.gambiae AgaP_AGAP011036 4577553   XP_001237042 39
D.melanogaster Pi3K68D 39329   NP_001163420 39
C.elegans F39B1.1 181618   NP_510529 31

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)