Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. NDUFS2, NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
Sequence ID:NM_001166159
NM_004550
RefSeqGene ID:NG_013352
Entrez Gene ID:4720
Ensembl ID:ENSG00000158864

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
MITOCHONDRIAL COMPLEX I DEFICIENCYFOXRED1
NDUFA1
NDUFA11
NDUFAF1
NDUFAF2
NDUFAF3
NDUFAF4
NDUFAF5
NDUFB3
NDUFS1
NDUFS1
NDUFS4
NDUFS6
NDUFV1
NDUFV2
NUBPL

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 161172169 - 161184184

 Exon Info From UCSC:
NM_001166159
NM_004550

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2899956Full LengthBC000170NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
3138814Full LengthBC001456NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
4131430Full LengthBC008868NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004541  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001166159 NP_001159631      
NM_004550 NP_004541 O75306 EC 1.6.99.3
EC 1.6.5.3
Complex1_49kDa

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF050640 AAC27453 O75306 EC 1.6.99.3
EC 1.6.5.3
AF013160 AAC34362 O75306 EC 1.6.99.3
EC 1.6.5.3
BC000170 AAH00170 O75306 EC 1.6.99.3
EC 1.6.5.3
BC001456 AAH01456 O75306 EC 1.6.99.3
EC 1.6.5.3
BC008868 AAH08868 O75306 EC 1.6.99.3
EC 1.6.5.3
DQ894087 ABM85013    
AK222618 BAD96338 Q53HG2  
AK301641 BAH13528 B7Z792  
AK315977 BAH14348 B7Z9L2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NDUFS2 NP_004541 M.musculus Ndufs2 226646 Gene Info NP_694704 92
R.norvegicus Ndufs2 289218   NP_001011907 92
A.gambiae AgaP_AGAP000794 1272388   XP_311336 78
A.gambiae AgaP_AGAP006891 1270187   XP_308864 76
D.melanogaster CG1970 43798   NP_651926 76
C.elegans nduf-2.2 188912   NP_498423 74
C.elegans gas-1 181646   NP_510569 74
N.crassa NCU02534 3881799   XP_965665 72
A.thaliana nad7 814592   NP_085511 71

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)