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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. DYRK2, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
Sequence ID:NM_003583
Entrez Gene ID:8445
Ensembl ID:ENSG00000127334

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q15Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 68056251 - 68058942

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3831977Full LengthBC005809dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
4139392Full LengthBC006375dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003574  

Protein Infomation

NM_003583 NP_003574 Q92630 EC Pkinase
NM_006482 NP_006473 Q92630 EC  

Related Sequences

BC005809 AAH05809 Q92630 EC
BC006375 AAH06375 Q92630 EC
JF432719 ADZ15936    
AK313937 BAG36656 Q92630 EC
Y09216 CAA70418 Q92630 EC
Y13493 CAA73885 Q92630 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens DYRK2 NP_006473 R.norvegicus Dyrk2 314862   NP_001101570 98
M.musculus Dyrk2 69181 Gene Info NP_001014412 97
D.melanogaster Dyrk3 3885567   NP_001033810 73
A.gambiae AgaP_AGAP008241 1277739   XP_317229 65
C.elegans mbk-2 178250   NP_001023207 63
S.pombe pom1 2541889   NP_592974 46
N.crassa NCU06638 3877025   XP_960871 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)