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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PLK4, Polo-like kinase 4
Sequence ID:NM_014264
NM_001190799
NM_001190801
Entrez Gene ID:10733
Ensembl ID:ENSG00000142731

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:4q28Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 128802100 - 128819927

 Exon Info From UCSC:
NM_014264
NM_001190799
NM_001190801

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5273226Full LengthBC036023polo-like kinase 4 (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_055079  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001190799 NP_001177728      
NM_001190801 NP_001177730      
NM_014264 NP_055079 O00444 EC 2.7.11.21 Pkinase
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC036023 AAH36023 O00444 EC 2.7.11.21
DQ894189 ABM85115    
AB006972 BAB69958 O00444 EC 2.7.11.21
AK314238 BAG36907 O00444 EC 2.7.11.21
AK302858 BAH13823 O00444 EC 2.7.11.21
AK303399 BAH13953 O00444 EC 2.7.11.21
Y13115 CAA73575 O00444 EC 2.7.11.21
Z25433 CAA80920 Q15455  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PLK4 NP_055079 M.musculus Plk4 20873 Gene Info NP_035625 83
R.norvegicus Plk4 310344   NP_001101139 82
A.gambiae AgaP_AGAP012499 1268576   XP_307136 49
D.melanogaster SAK 40384   NP_649324 47

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)