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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SKP1, S-phase kinase-associated protein 1
Sequence ID:NM_006930
Entrez Gene ID:6500
Ensembl ID:ENSG00000113558

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 133493164 - 133497588

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4053593Full LengthBC009839S-phase kinase-associated protein 1
4243711Full LengthBC020798S-phase kinase-associated protein 1
5203008Full LengthBC025673S-phase kinase-associated protein 1
6672613Full LengthBC065730S-phase kinase-associated protein 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_733779  NP_008861  

Protein Infomation

NM_006930 NP_008861   Skp1
NM_170679 NP_733779 P63208 Skp1

Related Sequences

U37558 AAA79202 P63208
U33760 AAC50241 P63208
BC009839 AAH09839 P63208
BC020798 AAH20798 P63208
BC025673 AAH25673 P63208
BC065730 AAH65730 P63208
DQ891512 ABM82438  
DQ894703 ABM85629  
EU831713 ACE86547  
EU831628 ACE87228  
Z47087 CAA87392 P63208

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SKP1 NP_733779 M.musculus Skp1a 21402 Gene Info NP_035673 99
R.norvegicus Skp1 287280   NP_001007609 99
A.gambiae AgaP_AGAP008719 1275570   XP_314827 85
D.melanogaster skpA 31016   NP_726695 77
C.elegans skr-1 172775   NP_492513 72
C.elegans skr-2 172773   NP_492512 65
A.thaliana ASK2 834224   NP_568603 62
N.crassa NCU08991 3875176   XP_959019 59
S.pombe skp1 2540917   NP_595455 58
S.cerevisiae SKP1 851928   NP_010615 55

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta