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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CFL1, cofilin 1 (non-muscle)
Sequence ID:NM_005507
Entrez Gene ID:1072
Ensembl ID:ENSG00000172757

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 65622289 - 65626886

NM_005507 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
66386562228665622918
6397156562312465623200
71610236562340565623712
102412606562556765625803

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3448134Full LengthBC018256cofilin 1 (non-muscle)
3538185Full LengthBC012318cofilin 1 (non-muscle)
3862540Full LengthBC012265cofilin 1 (non-muscle)
4079579Full LengthBC011005cofilin 1 (non-muscle)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005498  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005507 NP_005498 P23528 Cofilin_ADF

Related Sequences

 
mRNAGenPeptSwissProt
U21909 AAA64501 P23528
BC011005 AAH11005 P23528
BC012265 AAH12265 P23528
BC012318 AAH12318 P23528
BC018256 AAH18256 P23528
BT006846 AAP35492 P23528
DQ891769 ABM82695  
EU176624 ABW03425  
D00682 BAA00589 P23528
AK097690 BAG53513 P23528
X95404 CAA64685 P23528

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CFL1 NP_005498 M.musculus Cfl1 12631 Gene Info NP_031713 99
R.norvegicus Cfl1 29271   NP_058843 99

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)