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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PLA2G6, phospholipase A2, group VI (cytosolic, calcium-independent)
Sequence ID:NM_001004426
NM_001199562
NM_003560
RefSeqGene ID:NG_007094
Entrez Gene ID:8398
Ensembl ID:ENSG00000184381

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
INFANTILE NEUROAXONAL DYSTROPHY 1 
KARAK SYNDROME 
PARKINSON DISEASE 14 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 38507501 - 38577763

 Exon Info From UCSC:
NM_001004426
NM_003560

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5166749Full LengthBC036742phospholipase A2, group VI (cytosolic, calcium-independent)
5175768Full LengthBC051904phospholipase A2, group VI (cytosolic, calcium-independent)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001004426  NP_003551  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001004426 NP_001004426     Ank
Patatin
NM_001199562 NP_001186491      
NM_003560 NP_003551 O60733 EC 3.1.1.4 Ank
Patatin

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF064594 AAC97486 O60733 EC 3.1.1.4
AF102988 AAD41722 O60733 EC 3.1.1.4
AF102989 AAD41723 O60733 EC 3.1.1.4
BC036742 AAH36742 O60733 EC 3.1.1.4
BC051904 AAH51904 O60733 EC 3.1.1.4
AK290825 BAF83514 A8K460  
AK291212 BAF83901 O60733 EC 3.1.1.4
AK096521 BAG53314 B3KU52  
AK300459 BAH13289 B7Z6K3  
AL080187 CAB45768 O60733 EC 3.1.1.4
CR456543 CAG30429 O60733 EC 3.1.1.4
CU013143 CAK54574    
CU013431 CAK54873    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PLA2G6 NP_003551 R.norvegicus Pla2g6 360426   NP_001005560 90
M.musculus Pla2g6 53357 Gene Info NP_058611 89
D.melanogaster iPLA2-VIA 39160   NP_729565 40
A.gambiae AgaP_AGAP004812 1278413   XP_317997 38
C.elegans F47A4.5 181196   NP_509647 30
C.elegans W07A8.2 180354   NP_001123029 29

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)