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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MMP12, matrix metallopeptidase 12 (macrophage elastase)
Sequence ID:NM_002426
RefSeqGene ID:NG_032936
Entrez Gene ID:4321

Database Links

UniGeneEntrez GeneOMIMHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:11q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 102733830 - 102745713

 Exon Info From UCSC:
NM_002426

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8327769Full LengthBC112301matrix metallopeptidase 12 (macrophage elastase)
9052287Full LengthBC143773matrix metallopeptidase 12 (macrophage elastase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002417  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002426 NP_002417 P39900 EC 3.4.24.65 Hemopexin
Peptidase_M10
PG_binding_1

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L23808 AAA58658 P39900 EC 3.4.24.65
BC112301 AAI12302 P39900 EC 3.4.24.65
BC143773 AAI43774 P39900 EC 3.4.24.65
HQ258263 ADR83017    
AK313959 BAG36675 P39900 EC 3.4.24.65

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MMP12 NP_002417 R.norvegicus Mmp12 117033   NP_446415 64
M.musculus Mmp12 17381 Gene Info NP_032631 63

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)