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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. EIF2B4, eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
Sequence ID:NM_001034116
NM_015636
NM_172195
RefSeqGene ID:NG_009305
Entrez Gene ID:8890
Ensembl ID:ENSG00000115211

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
LEUKOENCEPHALOPATHY WITH VANISHING WHITE MATTEREIF2B1
EIF2B2
EIF2B3
EIF2B5

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p23.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 27587222 - 27593200

 Exon Info From UCSC:
NM_001034116
NM_015636
NM_172195

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3534267Full LengthBC001870eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
30377783Full LengthBC091502eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_056451  NP_751945  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001034116 NP_001029288 Q9UI10  
NM_015636 NP_056451   IF-2B
NM_172195 NP_751945   IF-2B

Related Sequences

 
mRNAGenPeptSwissProt
AF112207 AAF17195 Q9UI10
AF218009 AAG17251 Q9HBP7
BC001870 AAH01870 Q9UI10
BC091502 AAH91502 Q9UI10
AF057699 AAQ13438 Q71US4
JQ991007 AFM43698 F8W8L6
AB209532 BAD92769 Q59FC8
AK300734 BAG62407 B4DUP5
AL050109 CAB43277 Q9Y3W7
AJ011305 CAB57260 Q9UI10
AJ011306 CAB57261 Q9UI10

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EIF2B4 NP_751945 R.norvegicus Eif2b4 117019   NP_446402 88
M.musculus Eif2b4 13667 Gene Info NP_001120828 88
D.melanogaster eIF2B-delta 37706   NP_611790 46
S.cerevisiae GCD2 852974   NP_011597 44
A.gambiae AgaP_AGAP005937 3290072   XP_556607 44
A.thaliana AT1G48970 841319   NP_175327 43
A.thaliana AT5G38640 833854   NP_198680 43
S.pombe tif224 2542064   NP_594503 42
C.elegans F11A3.2 179331   NP_001023784 25

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta