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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. METTL3, Methyltransferase like 3
Sequence ID:NM_019852
RefSeqGene ID:NG_001332
Entrez Gene ID:56339
Ensembl ID:ENSG00000165819

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q11.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 21966288 - 21979440

 Exon Info From UCSC:
NM_019852

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2821235Full LengthBC001650methyltransferase like 3
2821235Full LengthBC003031methyltransferase like 3
6081642Full LengthBC052244methyltransferase like 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_062826  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_019852 NP_062826 Q86U44 EC 2.1.1.62 MT-A70

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC001650 AAH01650 Q86U44 EC 2.1.1.62
BC003031 AAH03031 Q86U44 EC 2.1.1.62
BC052244 AAH52244 Q86U44 EC 2.1.1.62
EU446825 ABZ92354    
AK093509 BAG52732 B3KSH0  
AK300289 BAG62046 B4DTN4  
AK304251 BAG65118 B4E2F6  
AK304570 BAG65361 B4E349  
BX247964 CAD62303 Q86U44 EC 2.1.1.62

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens METTL3 NP_062826 M.musculus Mettl3 56335 Gene Info NP_062695 97
R.norvegicus Mettl3 361035   NP_001019965 97
A.gambiae AgaP_AGAP002895 1273072   XP_312015 54
D.melanogaster CG5933 42844   NP_651204 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)