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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SRP54, signal recognition particle 54kDa
Sequence ID:NM_001146282
Entrez Gene ID:6729
Ensembl ID:ENSG00000100883

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 35452197 - 35498544

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3343314Full LengthBC000652signal recognition particle 54kDa
3446599Full LengthBC003389signal recognition particle 54kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003127  

Protein Infomation

NM_001146282 NP_001139754    
NM_003136 NP_003127 P61011 SRP54

Related Sequences

U51920 AAC50994 P61011
BC000652 AAH00652 P61011
BC003389 AAH03389 P61011
JF432694 ADZ15911  
AK312853 BAG35706 P61011
AK293319 BAG56838 B4DDS7
AK300824 BAG62478 P61011

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SRP54 NP_003127 M.musculus Srp54a 24067 Gene Info NP_036029 100
M.musculus Srp54b 665155 Gene Info NP_001093579 100
R.norvegicus Srp54 116650   NP_446323 100
A.gambiae AgaP_AGAP004610 1275923   XP_315212 80
D.melanogaster Srp54k 38593   NP_523931 77
C.elegans F21D5.7 259584   NP_501507 72
A.thaliana AT1G48900 841312   NP_564535 59
N.crassa NCU09696 3876791   XP_960643 57
S.pombe srp54 2539290   NP_588209 55
P.falciparum PF14_0477 812059   XP_001348651 52
S.cerevisiae SRP54 856203   NP_015413 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)