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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SHH, sonic hedgehog
Sequence ID:NM_000193
RefSeqGene ID:NG_007504
Entrez Gene ID:6469
Ensembl ID:ENSG00000164690

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
COLOBOMA, OCULARGDF6
PAX6
PAX6
HOLOPROSENCEPHALY-3 
MICROPHTHALMIA WITH COLOBOMA 5 
POLYDACTYLY, PREAXIAL TYPE IILMBR1
SCHIZENCEPHALYEMX2
SIX3
SINGLE MEDIAN MAXILLARY CENTRALINCISOR 

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q36Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 155595654 - 155601758

NM_000193 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1863155595557155596419
8641125155598989155599250
11261576155604516155604966

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40080739BC111925sonic hedgehog homolog (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000184  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000193 NP_000184 Q15465 Hint
HH_signal

Related Sequences

 
mRNAGenPeptSwissProt
L38518 AAA62179 Q15465
BC111925 AAI11926  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SHH NP_000184 M.musculus Shh 20423 Gene Info NP_033196 93
R.norvegicus Shh 29499   NP_058917 93
A.gambiae AgaP_AGAP001412 1281764   XP_321721 55
D.melanogaster hh 42737   NP_001034065 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta