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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PICALM, phosphatidylinositol binding clathrin assembly protein
Sequence ID:NM_001008660
NM_001206946
NM_001206947
NM_007166
RefSeqGene ID:NG_028942
Entrez Gene ID:8301
Ensembl ID:ENSG00000073921

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
LEUKEMIA, ACUTE MYELOGENOUSARHGEF12
CBFB
CEBPA
CHIC2
ETV6
FLT3
GATA2
GMPS
JAK2
KIT
LPP
MLF1
MLLT10
NPM1
NSD1
NUP214
RUNX1
RUNX1
SH3GL1
TERT
WHSC1L1

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q14Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 85668730 - 85780139

 Exon Info From UCSC:
NM_001008660
NM_007166

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5112878Full LengthBC064357phosphatidylinositol binding clathrin assembly protein
5537605Full LengthBC048259phosphatidylinositol binding clathrin assembly protein
6183858Full LengthBC073961phosphatidylinositol binding clathrin assembly protein

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_009097  NP_001008660  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001008660 NP_001008660   ANTH
NM_001206946 NP_001193875    
NM_001206947 NP_001193876    
NM_007166 NP_009097 Q13492 ANTH

Related Sequences

 
mRNAGenPeptSwissProt
U45976 AAB07762 Q13492
AF060939 AAC16711 Q13492
AF060940 AAC16712 Q13492
BC048259 AAH48259 Q13492
BC064357 AAH64357 Q13492
BC073961 AAH73961 Q13492
AY326466 AAR99516 Q6EHZ1
EF051633 ABK54356 A0MWC9
AB210017 BAE06099 Q4LE54
AK291414 BAF84103 A8K5U9
AK297062 BAG59583 B4DLM1
AK300275 BAG62035 B4DTM3
AB451308 BAG70122 B5BU72

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PICALM NP_009097 R.norvegicus Picalm 89816   NP_446006 98
M.musculus Picalm 233489 Gene Info NP_666306 98
A.gambiae AgaP_AGAP010087 1279517   XP_319245 49
D.melanogaster lap 40863   NP_001163538 48
S.cerevisiae YAP1801 856566   NP_012031 27
S.cerevisiae YAP1802 853157   NP_011757 25

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta