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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. MOCS2, molybdenum cofactor synthesis 2
Sequence ID:NM_004531
NM_176806
RefSeqGene ID:NG_008435
Entrez Gene ID:4338
Ensembl ID:ENSG00000164172

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
MOLYBDENUM COFACTOR DEFICIENCY, TYPE AGPHN
MOCS1
MOCS1

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 52393897 - 52405575

 Exon Info From UCSC:
NM_004531
NM_176806

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5740329Full LengthBC046097molybdenum cofactor synthesis 2
30527619IncompleteBC095417molybdenum cofactor synthesis 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004522  NP_789776  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004531 NP_004522 O96007 EC 2.8.1.12 MoaE
NM_176806 NP_789776 O96033   ThiS

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF117815 AAD13296 O96033  
AF117815 AAD13297 O96007 EC 2.8.1.12
AF091871 AAD14598 O96033  
AF091871 AAD14599 O96007 EC 2.8.1.12
AF155659 AAF67478 O96007 EC 2.8.1.12
BC046097 AAH46097 O96007 EC 2.8.1.12
AK312887 BAG35735 O96007 EC 2.8.1.12
CR457172 CAG33453 O96007 EC 2.8.1.12

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MOCS2 NP_004522 R.norvegicus Mocs2 294753   NP_001007634 85
M.musculus Mocs2 17434 Gene Info NP_001106845 84
D.melanogaster CG42503 8674021   NP_651340 58
A.gambiae MOC2A_ANOGA_b 1274443   XP_313564 55
A.thaliana AT2G43760 818979   NP_001118518 51
C.elegans T27A3.6 188966   NP_491763 44
N.crassa NCU03170 3880716   XP_964576 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)