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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PYCR1, pyrroline-5-carboxylate reductase 1
Sequence ID:NM_006907
RefSeqGene ID:NG_023032
Entrez Gene ID:5831
Ensembl ID:ENSG00000183010

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q25.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 79890268 - 79894968

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3505512Full LengthBC001504pyrroline-5-carboxylate reductase 1
4420238Full LengthBC022244pyrroline-5-carboxylate reductase 1
5088067Full LengthBC071842pyrroline-5-carboxylate reductase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_008838  

Protein Infomation

NM_006907 NP_008838 P32322 EC F420_oxidored
NM_153824 NP_722546      

Related Sequences

M77836 AAA36407 P32322 EC
AF218000 AAG17242 P32322 EC
BC001504 AAH01504 P32322 EC
BC022244 AAH22244 Q8TBX0  
BC071842 AAH71842 P32322 EC
AY513285 AAT08038 Q2TU78  
HQ447821 ADQ32305    
HQ154643 ADU15815 E7D7X9  
HQ154644 ADU15816 E7D7Y0  
JF432573 ADZ15790    
AK297627 BAG60002 B4DMU0  
CR541769 CAG46568 P32322 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PYCR1 NP_008838 M.musculus Pycr1 209027 Gene Info NP_659044 92
R.norvegicus Pycr1 287877   NP_001099327 92
A.gambiae AgaP_AGAP002308 1273661   XP_312663 42
D.melanogaster P5cr 42284   NP_524400 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)