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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PDHB, pyruvate dehydrogenase (lipoamide) beta
Sequence ID:NM_000925
NM_001173468
NR_033384
RefSeqGene ID:NG_016860
Entrez Gene ID:5162
Ensembl ID:ENSG00000168291

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p21.1-p14.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 58413404 - 58419554

 Exon Info From UCSC:
NM_000925
NM_001173468

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2820672Full LengthBC000439pyruvate dehydrogenase (lipoamide) beta
2820672Full LengthBC001924pyruvate dehydrogenase (lipoamide) beta

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000916  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000925 NP_000916 P11177 EC 1.2.4.1 Transket_pyr
Transketolase_C
NM_001173468 NP_001166939      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M34479 AAA36428 P11177 EC 1.2.4.1
M19123 AAA60052 P11177 EC 1.2.4.1
M54788 AAA60053 P11177 EC 1.2.4.1
M34056 AAA60054 P11177 EC 1.2.4.1
M34055 AAA60233 P11177 EC 1.2.4.1
J03576 AAA88097 P11177 EC 1.2.4.1
BC000439 AAH00439 P11177 EC 1.2.4.1
BC001924 AAH01924 P11177 EC 1.2.4.1
DQ891366 ABM82292    
DQ894546 ABM85472    
AB209241 BAD92478 Q59G68  
AK313022 BAG35857 P11177 EC 1.2.4.1
AK293153 BAG56698 P11177 EC 1.2.4.1
X57778 CAA40924 P11177 EC 1.2.4.1
AL117618 CAB56017 P11177 EC 1.2.4.1
CR541911 CAG46709 P11177 EC 1.2.4.1
AM392999 CAL37877    
AM393278 CAL38156    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PDHB NP_000916 R.norvegicus Pdhb 289950   NP_001007621 94
M.musculus Pdhb 68263 Gene Info NP_077183 94
A.gambiae AgaP_AGAP010421 1272627   XP_311527 70
D.melanogaster CG11876 43437   NP_733265 68
C.elegans C04C3.3 177108   NP_500340 66
S.cerevisiae PDB1 852522   NP_009780 63
N.crassa NCU03004 3881540   XP_965390 62
A.thaliana MAB1 835157   NP_199898 61
S.pombe pdb1 2540273   NP_596272 60

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)