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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. IGF1, insulin-like growth factor 1 (somatomedin C)
Sequence ID:NM_000618
NM_001111283
NM_001111284
NM_001111285
RefSeqGene ID:NG_011713
Entrez Gene ID:3479
Ensembl ID:ENSG00000017427

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
GROWTH RETARDATION WITH DEAFNESS AND MENTAL RETARDATION DUE TOIGF1 DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q23.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 102792585 - 102874374

 Exon Info From UCSC:
NM_000618
NM_001111283
NM_001111284
NM_001111285

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8860206Full LengthBC148266insulin-like growth factor 1 (somatomedin C)
40129266Full LengthBC152321insulin-like growth factor 1 (somatomedin C)
100064018Full LengthBC160082insulin-like growth factor 1 (somatomedin C)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000609  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000618 NP_000609 Q5U743 Insulin
NM_001111283 NP_001104753    
NM_001111284 NP_001104754    
NM_001111285 NP_001104755 P05019  

Related Sequences

 
mRNAGenPeptSwissProt
M11568 AAA52539 P05019
M29644 AAA52543 Q9NP10
M27544 AAA52787 Q5U743
P05019
M37484 AAA52789 P05019
U40870 AAA96152 Q13429
BC148266 AAI48267 P05019
BC152321 AAI52322 Q5U743
BC160082 AAI60082  
AB209184 BAD92421 Q59GC5
AK312231 BAG35164  
X00173 CAA24998 Q5U743
P05019
X56773 CAA40092 Q5U743
P05019
X56774 CAA40093 P05019
X57025 CAA40342 Q5U743
P05019
CR541861 CAG46659 Q5U743

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IGF1 NP_000609 R.norvegicus Igf1 24482   NP_001075948 93
M.musculus Igf1 16000 Gene Info NP_034642 90

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta