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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ITSN1, intersectin 1 (SH3 domain protein)
Sequence ID:NM_001001132
RefSeqGene ID:NG_029504
Entrez Gene ID:6453
Ensembl ID:ENSG00000205726

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:21q22.1-q22.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:21: 35014945 - 35210796

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7469144Full LengthBC117560intersectin 1 (SH3 domain protein)
40073780Full LengthBC116185intersectin 1 (SH3 domain protein)
40073781Full LengthBC116186intersectin 1 (SH3 domain protein)
3878242IncompleteBC013578intersectin 1 (SH3 domain protein)
4443129IncompleteBC058925intersectin 1 (SH3 domain protein)
5784342IncompleteBC039036intersectin 1 (SH3 domain protein)
6420600IncompleteBC073744intersectin 1 (SH3 domain protein)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003015  NP_001001132  

Protein Infomation

NM_001001132 NP_001001132   SH3_1
NM_003024 NP_003015 Q15811 SH3_1

Related Sequences

U61166 AAC50592 Q15811
AF064243 AAC78610 Q15811
AF064244 AAC78611 Q15811
AF114487 AAD29952 Q15811
AF114488 AAD29953 Q15811
AF180522 AAD53183 Q15811
BC039036 AAH39036 Q8IWH9
BC058925 AAH58925 Q6PD56
BC073744 AAH73744 Q6GMY7
BC116185 AAI16186 Q14BD4
BC116186 AAI16187 Q14BD3
BC117560 AAI17561 Q15811
AY138139 AAN11307 Q8IWU0
AY254341 AAP13099 Q86VI9
AY340592 AAQ19991 Q7Z453
AY340593 AAQ19992 Q7Z452
AY603418 AAT28305 Q6J334
AY603419 AAT28306 Q6J333
AY605091 AAT36645 Q6J1T2
AY605092 AAT36646 Q6J1T1
DQ340865 ABC69037 Q2LAE2
DQ386455 ABD72328 Q20BK3
DQ679754 ABG74695 Q0PW97
DQ679755 ABG74696 Q0PW96
DQ679756 ABG74697 Q0PW95
DQ679757 ABG74698 Q0PW94
EU107386 ABV03351 A7XZY7
EU117382 ABV21755 A7Y322
EU120733 ABV24866 A8CTX8
EU120734 ABV24867 A8CTY3
EU120735 ABV24868 A8CTY7
EU120736 ABV24869 A8CTZ0
EU140799 ABV58335 A7Y322
EU140800 ABV58336 A8D7D0
EU152331 ABV69555 A8DCP3
EU191901 ABW71829 A8W608
GU939616 ADF97294 D6PAV9
GU939617 ADF97295 D6PAW0
GU939621 ADF97297 D6PAW2
AK300274 BAG62034 B4DTM2
BX538175 CAD98050 Q7Z328

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens ITSN1 NP_003015 M.musculus Itsn1 16443 Gene Info NP_034717 95
R.norvegicus Itsn1 29491   NP_001129568 95
A.gambiae AgaP_AGAP009037 1279996   XP_319789 40
D.melanogaster Dap160 35378   NP_477322 38
C.elegans itsn-1 178491   NP_503037 33

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)