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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. BTK, Bruton agammaglobulinemia tyrosine kinase
Sequence ID:NM_000061
RefSeqGene ID:NG_009616
Entrez Gene ID:695
Ensembl ID:ENSG00000010671

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
AGAMMAGLOBULINEMIA, X-LINKED 1 
AGAMMAGLOBULINEMIAAND ISOLATED HORMONE DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xq21.33-q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 100604858 - 100611150

 Exon Info From UCSC:
NM_000061

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40034287Full LengthBC109079Bruton agammaglobulinemia tyrosine kinase
40034289Full LengthBC109080Bruton agammaglobulinemia tyrosine kinase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000052  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000061 NP_000052 Q06187 EC 2.7.10.2 SH2
SH3_1
PH
BTK
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF153755 AAF37332 Q9P0L8  
AF153756 AAF37333 Q9NPI2  
AF153757 AAF37334 Q9NPI2  
AF153758 AAF37335 Q9P0L7  
AF153759 AAF37336 Q9NPI3  
AF153760 AAF37337 Q9NPI3  
AF153761 AAF37338 Q9P0L6  
AF153762 AAF37339 Q9P0L5  
AF153763 AAF37340 Q9P0L4  
AF153764 AAF37341 Q9P0L3  
AF153364 AAF61477 Q9P0M0  
BC109079 AAI09080 Q06187 EC 2.7.10.2
BC109080 AAI09081 Q06187 EC 2.7.10.2
AK314382 BAG37008 B2RAW1  
AK057105 BAG51864 Q5JY90  
X58957 CAA41728 Q06187 EC 2.7.10.2
AJ888377 CAI59836 Q572P4  
AJ888378 CAI59837 Q572P3  
AJ888380 CAI59839 Q572P1  
AJ888381 CAI59840 Q572P0  
AJ888376 CAI59842 Q572P5  
AM051275 CAJ19681 Q3MS97  
AM051276 CAJ19682 Q3MS96  
AM051277 CAJ19683 Q3MS95  
AM051278 CAJ19684 Q3MS94  
AM051279 CAJ19685 Q3MS93  
AM051280 CAJ19686 Q3MS92  
AM051281 CAJ19687 Q3MS91  
AM051282 CAJ19688 Q3MS90  
AM051283 CAJ19689 Q3MS89  
AM051284 CAJ19690 Q3MS88  
AM051285 CAJ19691 Q3MS87  
AM051286 CAJ19692 Q3MS86  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens BTK NP_000052 M.musculus Btk 12229 Gene Info NP_038510 98
R.norvegicus Btk 367901   NP_001007799 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta