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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. NLRP3, NLR family, pyrin domain containing 3
Sequence ID:NM_001079821
NM_001127461
NM_001127462
NM_001243133
NM_004895
NM_183395
RefSeqGene ID:NG_007509
Entrez Gene ID:114548
Ensembl ID:ENSG00000162711

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CINCA SYNDROME 
COLD-INDUCED AUTOINFLAMMATORY SYNDROME, FAMILIAL 
MUCKLE-WELLS SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q44Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 247579482 - 247612119

 Exon Info From UCSC:
NM_001079821
NM_001127461
NM_001127462
NM_004895
NM_183395

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9051864Full LengthBC143359NLR family, pyrin domain containing 3
9051867Full LengthBC143362NLR family, pyrin domain containing 3
9051868Full LengthBC143363NLR family, pyrin domain containing 3
40125762Full LengthBC117211NLR family, pyrin domain containing 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_899632  NP_004886  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001079821 NP_001073289    
NM_001127461 NP_001120933    
NM_001127462 NP_001120934    
NM_001243133 NP_001230062    
NM_004895 NP_004886 Q96P20 LRR_1
PAAD_DAPIN
NACHT
NM_183395 NP_899632   LRR_1
PAAD_DAPIN
NACHT

Related Sequences

 
mRNAGenPeptSwissProt
AF054176 AAC39910 Q96P20
BC117211 AAI17212 Q96P20
BC143359 AAI43360 B7ZKS9
BC143362 AAI43363 Q96P20
BC143363 AAI43364 Q96P20
AF418985 AAL14640 Q96P20
AF410477 AAL33908 Q96P20
AF427617 AAL33911 Q96P20
AF420469 AAL65136 Q96P20
AF468522 AAL78632 Q96P20
AY092033 AAM14669 Q96P20
AY422168 AAQ98889 Q96P20
AB208891 BAD92128 Q96P20
AK314998 BAG37494 B2RC97

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NLRP3 NP_004886 M.musculus Nlrp3 216799 Gene Info NP_665826 83
R.norvegicus Nlrp3 287362   XP_220513 82

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)