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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. RAF1, V-raf-1 murine leukemia viral oncogene homolog 1
Sequence ID:NM_002880
RefSeqGene ID:NG_007467
Entrez Gene ID:5894
Ensembl ID:ENSG00000132155

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
LEOPARD SYNDROME 2 
NOONAN SYNDROME 5 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 12629484 - 12631279

 Exon Info From UCSC:
NM_002880

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3904404Full LengthBC018119v-raf-1 murine leukemia viral oncogene homolog 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002871  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002880 NP_002871 P04049 EC 2.7.11.1 Pkinase
C1_1
RBD

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC018119 AAH18119 P04049 EC 2.7.11.1
AK312248 BAG35180 P04049 EC 2.7.11.1
AK303561 BAG64584 B4E0X2  
AK303920 BAG64848 B4E1N6  
X03484 CAA27204 P04049 EC 2.7.11.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RAF1 NP_002871 M.musculus Raf1 110157 Gene Info NP_084056 98
R.norvegicus Raf1 24703   NP_036771 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta