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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EIF5B, eukaryotic translation initiation factor 5B
Sequence ID:NM_015904
Entrez Gene ID:9669
Ensembl ID:ENSG00000158417

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 99953867 - 100016241

 Exon Info From UCSC:
NM_015904

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5496504Full LengthBC032639eukaryotic translation initiation factor 5B
4041983IncompleteBC006970eukaryotic translation initiation factor 5B
4804924IncompleteBC022260eukaryotic translation initiation factor 5B

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_056988  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_015904 NP_056988 O60841 GTP_EFTU
MMR_HSR1
GTP_EFTU_D2

Related Sequences

 
mRNAGenPeptSwissProt
AF078035 AAD16006 O60841
BC006970 AAH06970 A0JLR8
BC022260 AAH22260 Q05CQ1
BC032639 AAH32639 Q8N5A0
AB018284 BAA34461 O60841
AK001386 BAG50898 B3KM86
AJ006412 CAA07018 O60841
AJ006776 CAB44357 O60841
AL133563 CAB63717 O60841

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EIF5B NP_056988 M.musculus Eif5b 226982 Gene Info NP_938045 92
R.norvegicus Eif5b 308306   NP_001103611 91
A.gambiae AgaP_AGAP004824 1278404   XP_317984 62
D.melanogaster eIF5B 44261   NP_651974 56
C.elegans iffb-1 175353   NP_497536 47
S.pombe SPAC56F8.03 2543241   NP_593218 47
N.crassa NCU05270 3877875   XP_961727 47
S.cerevisiae FUN12 851196   NP_009365 46
P.falciparum PFF0345w 3885886   XP_966060 45
A.thaliana AT1G76810 844015   NP_177807 44
A.thaliana AT1G21160 838712   NP_173540 43
A.thaliana AT1G76720 844006   NP_177798 43
A.thaliana AT1G76820 844016   NP_565140 11

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)