Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PDCD1, programmed cell death 1
Sequence ID:NM_005018
RefSeqGene ID:NG_012110
Entrez Gene ID:5133
Ensembl ID:ENSG00000188389

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
?SYSTEMIC LUPUS ERYTHEMATOSUS, OR PROTECTION AGAINSTBANK1
C4A
C4A
DNASE1
DNASE1
FASLG
FCGR2B
FCGR3A
ITGAX
PTPN22
STAT4
STAT4
TREX1
TREX1
TREX1
MULTIPLE SCLEROSISCD24
CIITA
HLA-DQB1
HLA-DQB1
HLA-DRB1
HLA-DRB1
HLA-DRB1
IL7R
PTPRC
SYSTEMIC LUPUS ERYTHEMATOSUS 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q37.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 242793209 - 242801060

NM_005018 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
51420242792033242793448
14211455242794100242794134
14561611242794349242794504
16121971242794772242795131
19722115242800914242801057

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30915198Full LengthBC074740programmed cell death 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005009  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005018 NP_005009 Q15116 V-set

Related Sequences

 
mRNAGenPeptSwissProt
U64863 AAC51773 Q15116
BC074740 AAH74740 Q15116
AY206416 AAO25116 Q86TL7
AY238517 AAO63583 Q15116
AY322430 AAP85379 Q7Z5I0
AK313848 BAG36577 Q15116

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PDCD1 NP_005009 R.norvegicus Pdcd1 301626   NP_001100397 62
M.musculus Pdcd1 18566 Gene Info NP_032824 60

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)