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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. RAB7A, RAB7A, member RAS oncogene family
Sequence ID:NM_004637
RefSeqGene ID:NG_008070
Entrez Gene ID:7879
Ensembl ID:ENSG00000075785

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 128514210 - 128532265

NM_004637 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2821435Full LengthBC008721RAB7A, member RAS oncogene family
3882701Full LengthBC013728RAB7A, member RAS oncogene family

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004628  

Protein Infomation

NM_004637 NP_004628 P51149 Ras

Related Sequences

U44104 AAA86640 P51149
AF119891 AAF69645 Q9P156
BC008721 AAH08721 P51149
BC013728 AAH13728 P51149
AF498942 AAM21090 P51149
AK290721 BAF83410 P51149
AK298344 BAG60591 B4DPH9
BX537775 CAD97836 Q7Z680

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens RAB7A NP_004628 R.norvegicus Rab7a 29448   NP_076440 100
M.musculus Rab7 19349 Gene Info NP_033031 100
A.gambiae AgaP_AGAP001617 1281557   XP_321482 83
N.crassa NCU03711 3877651   XP_961487 78
D.melanogaster Rab7 42841   NP_524472 76
A.thaliana RAB7B 821415   NP_188512 69
A.thaliana RABG3E 841353   NP_001031161 68
S.pombe ypt7 2540763   NP_596307 67
S.cerevisiae YPT7 855012   NP_013713 65

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta