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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. AXIN2, axin 2
Sequence ID:NM_004655
RefSeqGene ID:NG_012142
Entrez Gene ID:8313
Ensembl ID:ENSG00000168646

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
COLON CANCERAKT1
APC
APC
AURKA
BCL10
BUB1B
CCND1
EP300
FGFR3
FLCN
MLH3
NRAS
ODC1
PDGFRL
PIK3CA
PIK3CA
PLA2G2A
PTPRJ
SMAD7
TLR2
TLR4
TP53
TP53
OLIGODONTIA-COLORECTAL CANCERSYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q23-q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 63524682 - 63532492

 Exon Info From UCSC:
NM_004655

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8069039Full LengthBC101533axin 2
9051745Full LengthBC143244axin 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004646  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_004655 NP_004646 Q5H9R8 RGS
DIX

Related Sequences

 
mRNAGenPeptSwissProt
AF078165 AAD20976 Q9Y2T1
AF205888 AAF22799 Q9Y2T1
BC006295 AAH06295 Q9BRF5
BC101533 AAI01534 Q9Y2T1
BC143244 AAI43245 B7ZKL5
AB052751 BAB19762 Q9Y2T1
CR933657 CAI45956 Q5H9R8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AXIN2 NP_004646 R.norvegicus Axin2 29134   NP_077331 91
M.musculus Axin2 12006 Gene Info NP_056547 91

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)