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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. GRHPR, Glyoxylate reductase/hydroxypyruvate reductase
Sequence ID:NM_012203
RefSeqGene ID:NG_008135
Entrez Gene ID:9380
Ensembl ID:ENSG00000137106

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
HYPEROXALURIA, PRIMARY, TYPE II 

Cytogenetic Location (from UniGene)

Cytogenetic Location:9q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 37422697 - 37436985

NM_012203 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11243742270637422829
1252553742484137424971
2563283742591837425990
3294453742653437426650
4465343742848037428568
5356393742972837429832
6407753743050737430642
7769063743200437432134
90712353743665737436985

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3347232Full LengthBC000605glyoxylate reductase/hydroxypyruvate reductase
30364220IncompleteBC088360glyoxylate reductase/hydroxypyruvate reductase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_036335  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_012203 NP_036335 Q9UBQ7 EC 1.1.1.79
EC 1.1.1.81
2-Hacid_dh
2-Hacid_dh_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF146018 AAD45886 Q9UBQ7 EC 1.1.1.79
EC 1.1.1.81
AF113251 AAD54066 Q9UBQ7 EC 1.1.1.79
EC 1.1.1.81
AF134895 AAF00111 Q9UBQ7 EC 1.1.1.79
EC 1.1.1.81
AF113215 AAG39286 Q9UBQ7 EC 1.1.1.79
EC 1.1.1.81
BC000605 AAH00605 Q9UBQ7 EC 1.1.1.79
EC 1.1.1.81
BC088360 AAH88360 Q5M7Z5  
AK026287 BAB15430 Q9H636  
AK315690 BAG38053 Q9UBQ7 EC 1.1.1.79
EC 1.1.1.81
AM393403 CAL38281    
AM393629 CAL38505    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GRHPR NP_036335 M.musculus Grhpr 76238 Gene Info NP_525028 86
R.norvegicus Grhpr 680021   NP_001107226 86
D.melanogaster CG1236 40708   NP_649579 53
A.thaliana AT1G79870 844326   NP_178105 40

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)