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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. GNB5, guanine nucleotide binding protein (G protein), beta 5
Sequence ID:NM_006578
Entrez Gene ID:10681
Ensembl ID:ENSG00000069966

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q21.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 52414643 - 52472162

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3621195Full LengthBC013997guanine nucleotide binding protein (G protein), beta 5

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006569  NP_057278  

Protein Infomation

NM_006578 NP_006569   WD40
NM_016194 NP_057278 O14775 WD40

Related Sequences

AF017656 AAC63826 O14775
AF300650 AAG18444 O14775
BC011671 AAH11671 Q96F32
BC013997 AAH13997 O14775
AF501885 AAM15921 O14775
AK290330 BAF83019 A8K2R5
AK314775 BAG37312 B2RBR5
AK125702 BAG54236 B3KWS4
AL117471 CAB55946 O14775
AM393025 CAL37903  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens GNB5 NP_057278 M.musculus Gnb5 14697 Gene Info NP_034443 99
R.norvegicus Gnb5 83579   NP_113958 99
A.gambiae AgaP_AGAP012525 1273722   XP_312729 70
A.gambiae AgaP_AGAP010318 1280292   XP_320124 70
D.melanogaster Gbeta5 31744   NP_572452 69
C.elegans gpb-2 172483   NP_492072 65
S.cerevisiae STE4 854387   NP_014855 40

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)