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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CYP1B1, cytochrome P450, family 1, subfamily B, polypeptide 1
Sequence ID:NM_000104
RefSeqGene ID:NG_008386
Entrez Gene ID:1545
Ensembl ID:ENSG00000138061

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, nervous, pancreas, pancreatic islet, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
GLAUCOMA 1, OPEN ANGLE, EOPTN
WDR36
GLAUCOMA 1A, PRIMARY OPEN ANGLELMX1B
MYOC
GLAUCOMA 3A, PRIMARY OPEN ANGLE, CONGENITAL, JUVENILE, OR ADULTONSET 
PETERS ANOMALYPAX6
PAX6
PITX2
PITX2

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p22.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 38297643 - 38303293

NM_000104 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
737143829474538298452
371547583830148838302531
475948533830292238303016
485551603830301738303322

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4662252Full LengthBC012049cytochrome P450, family 1, subfamily B, polypeptide 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000095  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000104 NP_000095 Q53TK1
Q16678
EC 1.14.14.1 p450

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U03688 AAA19567 Q53TK1
Q16678
EC 1.14.14.1
BC012049 AAH12049 Q53TK1
Q16678
EC 1.14.14.1
BT019979 AAV38782 Q16678 EC 1.14.14.1
BT020001 AAV38804 Q5TZV6  
JF432813 ADZ16030    
AK312686 BAG35566 Q53TK1  
AK303862 BAG64801 B4E1I9  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CYP1B1 NP_000095 M.musculus Cyp1b1 13078 Gene Info NP_034124 81
R.norvegicus Cyp1b1 25426   NP_037072 80
A.thaliana TT7 830693   NP_196416 28

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)