Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SMAD6, SMAD family member 6
Sequence ID:NM_001142861
NM_005585
NR_027654
RefSeqGene ID:NG_012244
Entrez Gene ID:4091
Ensembl ID:ENSG00000137834

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:15q21-q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 66994669 - 67074326

 Exon Info From UCSC:
NM_001142861
NM_005585

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3632931Full LengthBC012986SMAD family member 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005576  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001142861 NP_001136333    
NM_005585 NP_005576 O43541 MH1
MH2

Related Sequences

 
mRNAGenPeptSwissProt
AF035528 AAB94137 O43541
AF043640 AAC00497 O43541
U59914 AAC50792 O43541
AF037469 AAC82331 O43541
BC012986 AAH12986 O43541
AM909653 CAP20377 O43541

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SMAD6 NP_005576 M.musculus Smad6 17130 Gene Info NP_032568 95
R.norvegicus Smad6 367100   NP_001102472 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta