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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. NEK2, NIMA (never in mitosis gene a)-related kinase 2
Sequence ID:NM_002497
NM_001204183
NM_001204182
RefSeqGene ID:NG_029112
Entrez Gene ID:4751
Ensembl ID:ENSG00000117650

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:1q32.2-q41Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 211836184 - 211848933

Transcript StartTranscript EndChromosomal Start Chromosomal End
1873211836121211836993
874999211840447211840572
10001219211842454211842673
12201346211843622211843748
13471429211844543211844625
14301670211846824211847064
16711888211847637211847854
18892130211848725211848966

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5541026Full LengthBC043502NIMA (never in mitosis gene a)-related kinase 2
5416586IncompleteBC052807NIMA (never in mitosis gene a)-related kinase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002488  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001204182 NP_001191111      
NM_001204183 NP_001191112      
NM_002497 NP_002488 P51955 EC 2.7.11.1 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U11050 AAA19558 P51955 EC 2.7.11.1
BC043502 AAH43502 P51955 EC 2.7.11.1
BC052807 AAH52807 P51955 EC 2.7.11.1
BC065932 AAH65932 P51955 EC 2.7.11.1
AY045701 AAK92212 P51955 EC 2.7.11.1
BT019729 AAV38534 P51955 EC 2.7.11.1
AY863109 AAW56418 P51955 EC 2.7.11.1
AK223353 BAD97073 P51955 EC 2.7.11.1
AK303092 BAG64202 B4DZU0  
Z25425 CAA80912 P51955 EC 2.7.11.1
Z29066 CAA82309 P51955 EC 2.7.11.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NEK2 NP_002488 R.norvegicus Nek2 114482   NP_446143 90
R.norvegicus LOC690209 690209   XP_345901 90
M.musculus Nek2 18005 Gene Info NP_035022 88
D.melanogaster Nek2 31696   NP_572415 44
S.pombe fin1 2542237   NP_593305 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)