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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PREX1, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Sequence ID:NM_020820
Entrez Gene ID:57580
Ensembl ID:ENSG00000124126

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:20q13.13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 47240792 - 47444283

 Exon Info From UCSC:
NM_020820

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4137162IncompleteBC009948phosphatidylinositol 3,4,5-trisphosphate-dependent RAC exchanger 1
6142666IncompleteBC053616phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
100061946BC156402phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_065871  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_020820 NP_065871 Q8TCU6 PH
DEP
RhoGEF

Related Sequences

 
mRNAGenPeptSwissProt
BC053616 AAH53616 Q8TCU6
BC156402 AAI56403  
AB037836 BAA92653 Q8TCU6
AL136579 CAB66514 Q8TCU6
AJ320261 CAC86401 Q8TCU6
AL832913 CAH10614 Q8TCU6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PREX1 NP_065871 M.musculus Prex1 277360 Gene Info NP_808450 91
R.norvegicus Prex1 311647   NP_001129190 91

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)